Healthy Volunteer Research Model

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CMORE for Healthy Volunteers

(6 days ago) Web3 Develop ethics and policy guidance for Phase I healthy volunteer research that a.) extrapolates from the model organism framework in Specific Aims 1 and 2, b.) is attentive to the structural features of Phase I …

https://cmore.web.unc.edu/

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Advancing Ethics and Policy for Healthy‐Volunteer …

(5 days ago) WebThe model‐organism framework for phase I research directs focus to the welfare concerns that accompany the long‐term confinement of healthy volunteers to a …

https://onlinelibrary.wiley.com/doi/10.1002/eahr.500001

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Healthy Volunteers as Model Organisms - UNC Center for …

(5 days ago) WebDevelop ethics and policy guidance for Phase I healthy volunteer research that a.) extrapolates from the model organism framework in Specific Aims 1 and 2, b.) is attentive to the structural …

https://bioethics.unc.edu/2017/09/05/healthy-volunteers-as-model-organisms/

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POLICY BRIEF Key Messages Recommendations - Global Code …

(5 days ago) WebHealthy Volunteer Registries can significantly reduce risks for healthy monitoring repeated clinical trials. model for participation in clinical trials provides additional protection. …

https://www.globalcodeofconduct.org/wp-content/uploads/2018/11/TRUST-Policy-Brief_-Healthy-Volunteers.pdf

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Advancing Ethics and Policy for Healthy-Volunteer …

(1 days ago) WebBy bringing these two research worlds together, we aim to illustrate how the model-organism framework can enhance healthy volunteers' welfare during trials, improve …

https://pubmed.ncbi.nlm.nih.gov/30744313/

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Pivotal Considerations for Optimal Deployment of …

(4 days ago) WebOpportunities for healthy volunteer clinical pharmacology studies in oncology drug development: targeted agents, immunomodulatory agents, and beyond The second presentation provided an overview of …

https://ascpt.onlinelibrary.wiley.com/doi/full/10.1111/cts.12703

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Phase I trial compensation: How much do healthy …

(2 days ago) WebAdvancing ethics and policy for healthy-volunteer research through a model-organism framework. Ethics Hum Res 2019; 41(1): 4–14. Crossref. Grady C, …

https://journals.sagepub.com/doi/abs/10.1177/17407745211011069

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Program for Healthy Volunteers Clinical Center Home Page

(3 days ago) WebYou can find information about research studies currently recruiting volunteers by viewing the clinical studies website. When searching the web site, type in …

https://www.cc.nih.gov/participate/studies/healthy_vol_prg.html

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Healthy Volunteers The Oxford Handbook of Research …

(2 days ago) WebHealthy people can be used to model normal physiological states for basic research or to compare with diseased patients, but they are also critical to testing drugs …

https://academic.oup.com/edited-volume/35413/chapter/303161536

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(PDF) Advancing Ethics and Policy for Healthy‐Volunteer …

(4 days ago) WebBy bringing these two research worlds together, we aim to illustrate how the model‐organism framework can enhance healthy volunteers’ welfare during trials, …

https://www.researchgate.net/publication/330592756_Advancing_Ethics_and_Policy_for_Healthy-Volunteer_Research_through_a_Model-Organism_Framework

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Advancing Ethics and Policy for Healthy‐Volunteer …

(9 days ago) WebBy mobilizing a model-organism framework for phase I trials, we employ concepts and mechanisms typical to animal research to query gaps in the human …

https://onlinelibrary.wiley.com/doi/abs/10.1002/eahr.500001

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The NIMH intramural healthy volunteer dataset: A comprehensive …

(Just Now) WebThe NIMH Healthy Research Volunteer Dataset is a collection of phenotypic data characterizing healthy research volunteers using clinical assessments …

https://www.nature.com/articles/s41597-022-01623-9

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Reviewing the role of healthy volunteer studies in drug development

(3 days ago) WebClinical drug development is divided into 4 phases. Phase 1 studies are designed to establish the safety and tolerability profile of an investigational drug and the …

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278009/

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Phase I trial compensation: How much do healthy volunteers …

(3 days ago) WebPhase I trials also frequently require healthy volunteers to accept intense medical and behavioral monitoring, including confinement in a residential research …

https://journals.sagepub.com/doi/full/10.1177/17407745211011069

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Healthy Volunteers Clinical Center Home Page

(4 days ago) WebWhen you select individual studies, carefully review the study overview and eligibility requirements. If you meet the eligibility requirements, call 1-800-411-1222 (TTY …

https://clinicalcenter.nih.gov/recruit/volunteers.html

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Healthy volunteers in first‐in‐human oncology drug development …

(1 days ago) Web1 BACKGROUND. First-in-human (FIH) phase 1 clinical studies have traditionally been conducted in healthy volunteers (HVs) in the majority of the therapeutics areas, but for oncology drugs with cytotoxic or highly immunosuppressive or immunogenic mechanisms of action, these studies have usually included cancer patients (CPs) with …

https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.15092

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Studies for Healthy Volunteers < Clinical Trials at Yale

(2 days ago) WebAddictive Behaviors, Alcohol Addiction Brief training for 18-26 year olds: Regulation of alcohol craving Principal Investigator: Hedy Kober. Diseases of the Cardiovascular …

https://medicine.yale.edu/ycci/clinicaltrials/categories/healthy_people/

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Empowering health volunteer’s through participatory action …

(7 days ago) WebThe aim of this study was empowering health volunteers through an action research. This participatory action research was conducted through two continuous …

https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-021-10878-7

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Healthy Volunteers in Research Kessler Foundation

(7 days ago) WebHealthy volunteers serve as controls in our research, completing the same tasks that volunteers with a disability will complete. By including volunteers with and without …

https://kesslerfoundation.org/healthy-volunteers-research

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Healthy volunteers' perceptions of risk in US Phase I clinical trials

(8 days ago) WebThere is limited research on healthy volunteers’ perceptions of the risks of Phase I clinical trials. In order to contribute empirically to long-standing ethical concerns …

https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002698

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Retaining public health volunteers beyond COVID-19 PLOS ONE

(3 days ago) WebThis research uses a local COVID-19 public health volunteering programme case study to explore the volunteer’s journey and perspective using volunteers’ reported experiences to consider the potential for volunteer retention and role expansion into other public health issues beyond the COVID-19 pandemic. Gaskin’s model of volunteer

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0294157

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Healthy Volunteer Studies - Participate in Research

(Just Now) WebParticipate in Researchis designed to connect potential volunteers with open research studies. We are looking for healthy volunteers just like you to help answer important …

https://www.iths.org/participate/studies/healthy-volunteers/

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Healthy Research Volunteers Require a Unique, Specific …

(2 days ago) WebJune 26, 2018. Volunteers for clinical research are "renting" out their bodies to help discover how the human body reacts to a device, drug, or therapeutic strategy. Healthy …

https://www.psychiatryadvisor.com/news/healthy-research-volunteers-require-a-unique-specific-compensation-model/

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RePORT 〉 RePORTER

(8 days ago) WebTo do so, this project has 3 primary aims: (1) Describe and normatively evaluate the limitations of current re- search oversight in Phase I trials by analyzing data on healthy …

https://reporter.nih.gov/project-details/9548221

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Adult Healthy Volunteer Studies Enrolling at Yale

(9 days ago) WebClinical trial looking for healthy volunteers. If you are 18 to 40 years old and are in good health, you may be eligible to participate in a free and confidential research …

https://medicine.yale.edu/news-article/adult-healthy-volunteer-studies-enrolling-at-yale/

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MSU ranked among Peace Corps’ top volunteer-producing …

(Just Now) WebJimmy Schneidewind is an alum of MSU’s James Madison College and a graduate of Waverly High School in Lansing, Michigan. He was a Peace Corps …

https://msutoday.msu.edu/news/2024/msu-ranked-among-peace-corps-top-volunteer-producing-institutions

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Healthy volunteers in first‐in‐human oncology drug …

(5 days ago) Web• Generally, inclusion of healthy volunteers in clinical trials with oncology compounds has been limited to clinical pharmacology studies. • Development of noncytotoxic therapeutics with a favourable safety profile provides an opportunity for con-sidering conduct of oncology FIH trials in healthy volunteers. What this study adds

https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/bcp.15092?download=true

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Healthy volunteers needed for a research study on cannabigerol

(2 days ago) WebHealthy volunteers needed for a research study on cannabigerol. Healthy adults age 18-55 are needed to take part in a Johns Hopkins research study. …

https://hub.jhu.edu/announcements/2024/05/22/healthy-volunteers-needed-for-a-research-study-on-cannabigerol-cbg/

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Five basic habits may hold the key to good mental health

(2 days ago) WebHealthy routines might include cooking and eating a healthy meal, having a regular bedtime and getting regular exercise. Meaningful activities give us a sense of …

https://lighthouse.mq.edu.au/article/may-2024/five-basic-habits-may-hold-the-key-to-good-mental-health

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Advancing Ethics and Policy for Healthy‐Volunteer Research …

(8 days ago) WebNonhuman animal research and phase I healthy-volunteer clinical trials are both critical components of testing the safety of investigational drugs as part of the development of …

https://pericles.pericles-prod.literatumonline.com/doi/abs/10.1002/eahr.500001

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GigaPath: Whole-Slide Foundation Model for Digital Pathology

(6 days ago) WebIn joint work with Providence Health System and the University of Washington, we have developed Prov-GigaPath, an open-access whole-slide pathology foundation …

https://www.microsoft.com/en-us/research/blog/gigapath-whole-slide-foundation-model-for-digital-pathology/

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Kinetical analysis of D-alanine upon oral intake medRxiv

(1 days ago) WebD-Alanine, a rare enantiomer of alanine in life, can potentially alleviate the worsening of viral infections and maintain circadian rhythm. This study aimed to analyze …

https://www.medrxiv.org/content/10.1101/2024.05.21.24307633v1

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Chronic wasting disease unlikely to move from animals to people

(2 days ago) WebSummary: A new study of prion diseases, using a human cerebral organoid model, suggests there is a substantial species barrier preventing transmission of chronic …

https://www.sciencedaily.com/releases/2024/05/240517164131.htm

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Mediterranean Diet May Help Slow Brain Aging - Healthline

(5 days ago) WebAnthony/Stocksy United. New research has found that nutrients found in the Mediterranean diet may slow cognitive decline. A nutrient profile of fatty acids, anti …

https://www.healthline.com/health-news/mediterranean-diet-slows-brain-aging

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