Impact Of Genetic Variation On Health

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Gene–environment interactions and their impact on human health

(3 days ago) WEBGene × environment interactions. While genetic and environmental factors can independently increase the risk of disease, the interactions between these risk factors (G × E) also have a profound influence on human health. An expanding number of …

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9801363/

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Gene–environment interactions and their impact on human health

(Just Now) WEBPaul et al. provide an in-depth review supporting the role of genetic variation in arsenic-induced toxicity, suggesting that the effects of arsenic on the …

https://www.nature.com/articles/s41435-022-00192-6

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Gene–environment interactions and their impact on human …

(4 days ago) WEBindependent impact of genetic variation and the environment. We next detail well-established G×E interactions that impact human health involving environmental …

https://www.nature.com/articles/s41435-022-00192-6.pdf

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Human genetic variation and health: new assessment approaches …

(2 days ago) WEBSo, in this case, the health effects of genetic variation in MTHFR are modulated by folate status. Together, these gene×environment interactions can …

https://academic.oup.com/bmb/article/69/1/215/523355

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Genetics Basics CDC - Centers for Disease Control and Prevention

(5 days ago) WEBGenes in Life was created by Genetic Alliance to answer your questions about health and genetics. Genetics Home Reference: Classroom Medline Plus: Genetics, developed and …

https://www.cdc.gov/genomics/about/basics.htm

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Genetics, Nutrition, and Health: A New Frontier in Disease Prevention

(6 days ago) WEBNutrigenetics studies the impact of genetic variation on an individual’s response to dietary nutrients, while nutrigenomics investigates how dietary components …

https://www.tandfonline.com/doi/full/10.1080/27697061.2023.2284997

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Exploring the effects of genetic variation on gene regulation in …

(4 days ago) WEBCancer is a complex disease involving strong interactions between genetic and environmental factors, and the second leading cause of death globally [1, 2].The …

https://bmcgenomdata.biomedcentral.com/articles/10.1186/s12863-021-01021-x

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Understanding the Role of Genetic Variants in Human Disease

(Just Now) WEBThe laboratory of Harry Ostrer, MD, uses modern genomics to elucidate the roles of human genetic variation in these processes. Dr. Ostrer and his team have developed …

https://www.einsteinmed.edu/departments/pathology/research/genetic-variants-human-disease/

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Genetics Basics Genomics and Your Health CDC

(6 days ago) WEBMedline Plus: Genetics This website has consumer-friendly information about the effects of genetic variation on human health. National Human Genome …

https://www.cdc.gov/genomics-and-health/about/index.html

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4 Genetics and Nutrition Diet and Health: Implications for …

(3 days ago) WEBPolicy Implications of Genetic Variations. Public health policies generally focus on the average human being, without considering genetic variation. Thus, dietary …

https://nap.nationalacademies.org/read/1222/chapter/6

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Genetics, environment and health disparities linked to increased …

(Just Now) WEBCitation: Genetics, environment and health disparities linked to increased stress and mental health challenges during adolescence (2024, May 16) retrieved 16 …

https://medicalxpress.com/news/2024-05-genetics-environment-health-disparities-linked.html

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Genomics of disease risk in globally diverse populations

(9 days ago) WEBStudies assessing genetic diversity among global populations 2,3,4 have laid the framework for understanding the impact of genetic variation on disease risk in …

https://www.nature.com/articles/s41576-019-0144-0

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Effects of landscape, resource use, and body size on genetic …

(4 days ago) WEBQuantifying genetic structure and levels of genetic variation are fundamentally important to predicting the ability of populations to persist in human …

https://onlinelibrary.wiley.com/doi/10.1002/ece3.11358

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Impacts of Variation in the Human Genome on Gene Regulation

(7 days ago) WEBImpact of Genetic Variation on Transcript Sequence. The impact of single-nucleotide variations on transcript coding sequence is well established. Such variation …

https://www.sciencedirect.com/science/article/pii/S0022283613004476

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The landscape of rare genetic variation associated with …

(6 days ago) WEBBackground Inflammatory bowel disease (IBD) and Parkinson’s disease (PD) are chronic disorders that have been suggested to share common pathophysiological …

https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-024-01335-2

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Cardiovascular Burden of the V142I Transthyretin Variant

(7 days ago) WEBThe median African genetic ancestry percentage for each cohort was determined. To further accommodate the age-related effects on outcomes, we used …

https://jamanetwork.com/journals/jama/fullarticle/2818877

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Study Suggests Genetics as a Cause, Not Just a Risk, for Some …

(4 days ago) WEBScientists are proposing a new way of understanding the genetics of Alzheimer’s that would mean that up to a fifth of patients would be considered to have a …

https://www.nytimes.com/2024/05/06/health/alzheimers-cause-gene-apoe4.html

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Gut microbial genetic variation modulates host lifespan, sleep, and

(1 days ago) WEBRecent studies have shown that gut microorganisms can modulate host lifespan and activities, including sleep quality and motor performance. However, the role of gut …

https://pubmed.ncbi.nlm.nih.gov/37550381/

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Impact of Genomic Variation on Function (IGVF) Consortium

(8 days ago) WEBNHGRI initiated a new program, the Impact of Genomic Variation on Function (IGVF) Consortium, to develop a framework for systematically understanding the effects of …

https://www.genome.gov/Funded-Programs-Projects/Impact-of-Genomic-Variation-on-Function-Consortium

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Mega study charts how genetic variants affect metabolism - Nature

(Just Now) WEBMega study charts how genetic variants affect metabolism. A genome-wide association study of metabolic biomarkers in 136,000 participants discovered more than …

https://www.nature.com/articles/d41586-024-00458-1

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The copy number variant architecture of psychopathology and …

(1 days ago) WEBImportance: Childhood is a crucial developmental phase for mental health and cognitive function, both of which are commonly affected in patients with psychiatric …

https://www.medrxiv.org/content/10.1101/2024.05.14.24307376v1

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Study identifies genetic link between inflammatory bowel disease …

(9 days ago) WEBMore information: Meltem Ece Kars et al, The landscape of rare genetic variation associated with inflammatory bowel disease and Parkinson's disease comorbidity, …

https://www.msn.com/en-us/health/other/study-identifies-genetic-link-between-inflammatory-bowel-disease-and-parkinson-s-disease/ar-BB1mne7h

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Understanding Human Genetic Variation - NIH …

(4 days ago) WEBDifferences that occur elsewhere in the DNA—in the vast majority of the DNA that has no known function—have no impact. Some genetic variation, however, can be positive, providing an advantage in changing …

https://www.ncbi.nlm.nih.gov/books/NBK20363/

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Factors associated with psychological distress during genetic

(Just Now) WEBFurthermore, individuals with low health motivation were more likely to exhibit high BDI scores (p < 0.001) and low STAI-T scores (p = 0.02). Common perceptions and …

https://link.springer.com/article/10.1007/s00520-024-08573-5

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Research shows impact of caregiving on parents' employment, …

(7 days ago) WEBThey estimated that 4.4% of children in the U.S. have a genetic condition—roughly 0.5% higher than what the 2021 study showed. Creel said her team …

https://medicalxpress.com/news/2024-05-impact-caregiving-parents-employment-health.html

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Dynamics of cognitive variability with age and its genetic - Nature

(Just Now) WEBContrary to previous reports from smaller studies, genetic risk factors for dementia, including APOE genotype and AD-PRS, have a minimal impact on cognition …

https://www.nature.com/articles/s41591-024-02960-5

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Identifying barriers to genetic testing in subspecialty cardiac care

(1 days ago) WEBBackground The utility of genetic testing in cardiovascular medicine is well-established in expert consensus statements for optimizing patient care. However, …

https://www.medrxiv.org/content/10.1101/2024.05.15.24307347v1

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Asymmetric stem cell division maintains the genetic - bioRxiv

(9 days ago) WEBOur experimental data and computational model both suggest that the rate of asymmetric division is proportional to the time a stem cell clone takes to expand. Taken …

https://www.biorxiv.org/content/10.1101/2024.05.16.594576v1

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Risk of ‘genetic discrimination’ by insurance companies is ruining

(8 days ago) WEBGenetic testing underpins vital branches of medical science. Our research shows the question of who can assess a person’s genomic data directly influences …

https://theconversation.com/risk-of-genetic-discrimination-by-insurance-companies-is-ruining-peoples-trust-in-vital-medical-science-230112

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Relationship between HLA genetic variations, COVID-19 vaccine

(Just Now) WEBHere, the authors use data from the UK Biobank linked to electronic health records to investigate the association between genetic variation in HLA alleles and …

https://www.nature.com/articles/s41467-024-48339-5

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About Triple-Negative Breast Cancer Breast Cancer CDC

(4 days ago) WEBOne is a protein called human epidermal growth factor ( HER2 ). If your cancer has any of these three locks, doctors have a few keys (like hormone therapy or …

https://www.cdc.gov/breast-cancer/about/triple-negative-breast-cancer.html

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The importance of genomic variation for biodiversity - Nature

(Just Now) WEBGenetic diversity influences biodiversity, and thus NCP, in two main ways: (1) through standing genetic variation (that is, the particular combination of genes and …

https://www.nature.com/articles/s41576-020-00288-7

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