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The impact of genomics on precision public health: …

WebThe field of precision public health is still in its infancy and genomics will be a major contributor to its growth in the next decade. The COVID-19 pandemic provides …

Actived: 6 days ago

URL: https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-021-00886-y

Home page Genome Medicine

WebAims and scope. Genome Medicine publishes important advances of broad interest in the application of genetics, genomics and multi-omics to understand, diagnose and treat …

Category: Medicine Go Health

Advancing precision public health using human …

WebPrecision public health is a relatively new field that integrates components of precision medicine, such as human genomics research, with public health concepts to …

Category: Medicine Go Health

The Human Genome Project: big science transforms …

WebThe Human Genome Project (HGP) has profoundly changed biology and is rapidly catalyzing a transformation of medicine [1–3].The idea of the HGP was first …

Category: Medicine Go Health

Translating the human microbiome: a path to improving …

Web14 Altmetric. Metrics. Translating the human microbiome in health and disease requires detailed information about each microbial member—from individual …

Category: Health Go Health

Population study of the gut microbiome: associations …

WebThe gut microbiome’s direct contribution to health and disease status has been well established. From its extensive metabolic and synthetic capabilities and its …

Category: Health Go Health

Integration of whole genome sequencing into a …

WebBackground We report the findings from 4437 individuals (3219 patients and 1218 relatives) who have been analyzed by whole genome sequencing (WGS) at the …

Category: Health Go Health

The healthy human microbiome Genome Medicine Full …

WebHumans are virtually identical in their genetic makeup, yet the small differences in our DNA give rise to tremendous phenotypic diversity across the human …

Category: Health Go Health

Exploiting genomics to mitigate the public health impact …

WebAntimicrobial resistance (AMR) is a major global public health threat, which has been largely driven by the excessive use of antimicrobials. Control measures are …

Category: Health Go Health

Gut microbiome-host interactions in health and disease

WebThe human intestine carries a vast and diverse microbial ecosystem that has co-evolved with our species and is essential for human health [1, 2].Mammals possess …

Category: Health Go Health

Genomics of circadian rhythms in health and disease

WebCircadian clocks are endogenous oscillators that control 24-h physiological and behavioral processes. The central circadian clock exerts control over myriad aspects …

Category: Health Go Health

The microbiome in precision medicine: the way forward

WebNovel associations between the human microbiome and health and disease are routinely emerging, and important host–microbiome interactions are targets for new …

Category: Health Go Health

Family history assessment significantly enhances delivery of …

WebFamily history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards …

Category: Health Go Health

Developmental origins of health and disease: reducing the burden …

WebDespite a wealth of underpinning experimental support, there has been considerable resistance to the concept that environmental factors acting early in life …

Category: Health Go Health

Impact of the gut microbiota on inflammation, obesity, and …

WebThe human gut harbors more than 100 trillion microbial cells, which have an essential role in human metabolic regulation via their symbiotic interactions with the host. …

Category: Health Go Health

Genomic surveillance of avian-origin influenza A viruses causing …

WebAvian influenza A viruses (AIVs) pose a threat to global health because of their sporadic zoonotic transmission and potential to cause pandemics. Genomic …

Category: Health Go Health

Causality in dietary interventions—building a case for gut …

WebCausality is the missing link in our understanding of the gut microbiome, nutrition, and health. The gut microbiome has been at the forefront of medical research …

Category: Nutrition, Medical Go Health

Clinical implications of host genetic variation and susceptibility to

WebSince the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights have been gained into virus biology and the host factors that modulate …

Category: Coronavirus Go Health

Systems medicine: the future of medical genomics and healthcare

WebHigh-throughput technologies for DNA sequencing and for analyses of transcriptomes, proteomes and metabolomes have provided the foundations for …

Category: Health Go Health

Targeting the microbiome: from probiotics to fecal microbiota

WebThe notion of “good microbes” that may benefit host health originated in the early twentieth century when live microbes contained in fermented foods were thought to …

Category: Food Go Health

Making sense of big data in health research: Towards an EU action …

WebOn 30 October 2015, the Health Directorate of the Directorate-General for Research and Innovation at the European Commission (EC), the executive body of the …

Category: Health Go Health

Metabolic control by the microbiome

WebThe interaction between the metabolic activities of the intestinal microbiome and its host forms an important part of health. The basis of this interaction is in part …

Category: Health Go Health

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