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What Does a Medical Statistician do

WebIt is the statistician’s job to allocate patients to the new treatment or to the placebo or control treatment. Treatments must be allocated at random so that the two groups are similar in every way except for the treatment they are given. You can do a simple randomisation by tossing a coin and assigning all those who get a head to the control

Actived: 7 days ago

URL: https://www.psiweb.org/careers/medicalstatistics/medical-statistics

Evolution of Medical Statistics

WebAs a result of Florence’s work, the department of Army Medical Statistics was set up and her legacy of evidence-based medicine led to a decline in preventable hospital deaths and greater awareness of the importance of statistics in medical research and beyond. In the 1870s and 1880s, Polymath Sir Francis Galton is credited with the first use

Category:  Medical,  Medicine Go Health

Evaluation of statistical software for federated analysis of …

WebDemonstration of federated execution; Proof of federated results being exact and non-disclosive; Availability of software either commercial or open source. more complex federated analysis – logistic regression. Step 1: Distribute initial coefficients 0.

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Pharmaceutical Statistics Journal

WebPharmaceutical Statistics is the official journal of PSI. The Journal publishes papers that share experiences in the practical application of statistics within the pharmaceutical industry. It covers all aspects of pharmaceutical statistical applications from discovery, through pre-clinical development, clinical development, post-marketing

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Health Technology Assessment (HTA) Training Course

WebMark Sculpher, Neil Hawkins. and members of the HTA SIG. This 2-day course will provide an introduction to the methods of health technology assessment. There will be a focus on how to estimate the costs and benefits of new interventions and analysis undertaken to support decisions about whether new interventions should be funded by …

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Combining RCT efficacy data and real-world evidence to …

WebContext •Pre-launch, RCT data on new drug available, but no (or insufficient) observational data on who the drug is prescribed to in routine practice •Four-step approach 1. Identify similar drug for which observational data is available 2. Quantify the impact of treatment, prognostic factors, effect modifiers on

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Home [www.psiweb.org]

WebThe purpose of the PFDD SIG is to connect statisticians in pharmaceutical industry roles who work on progressing the inclusion of patient-reported outcomes (PROs) and clinical outcome assessments (COAs) across all phases of drug development process to share their knowledge and also lead statistical thinking and methods to solve common statistical …

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About the Conference

WebThe PSI 2024 Conference will be held from Sunday 16th to Wednesday 19th June 2024 as a face to face conference at Beurs van Berlage in Amsterdam, Netherlands. PSI was founded in 1977 and members now span statisticians and other quantitative scientists with an interest in statistics working in all areas of drug development and healthcare

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Application of High-Dimensional Data to Drug Development

WebFrom Unsupervised to Supervised Learning: A case study 1. Started with a hypothesis on the molecular pathway and the targeted drug activity 2. An ex-vivo experiment was conducted:

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EU HTA Regulation

WebEU HTA external engagement. On 14th September 2022, we presented 2 posters at the 7th EFSPI workshop on Regulatory Statistics 2022.You can view the posters presented here --> EFSPI Regulatory HTA Workshop September 2022 - HTA SIG EU HTA Posters. On 14th November 2022, we hosted a webinar "Statistics in EU HTA - PICOs, Estimands & More!".

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Patient and Public Involvement Involving the patient in HTA

WebPatient involvement in HTA Source: Patients’ perspectives in HTA: a route to robust evidence and fair deliberation, Int. J. Tech Assess Health Care, 2010, 334-340 and Facey KM, Hansen HP & Single ANV (eds) Patient Involvement in Health Technology Assessment.

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Accurate Sample Size Calculations in Trials with Non …

WebWe therefore need to replace by an effective sample size. *Royston, Parmar BMC Medical Research Methodology 2013, 13:152. RMST. • On day 1, effective sample size is. but decreases over time due to censoring. The overall effective sample size can be viewed as a weighted average of the changing.

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PSI HTA SIG Webinar: Estimands, PICOs and Co.

WebIn HTA, the PICO framework is typically used to translate policy questions into research questions. PICOs consist of five components: (1) population; (2) intervention; (3) comparator (s); and (4) outcome. During the reimbursement process, the manufacturer typically submits an evidence dossier that addresses the research questions (s) included

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Adjusting for treatment switching in randomised controlled …

WebICER = Dominated. ICER = £71,648. ICER = £26,293. ICER = £72,274. ICER = £38,925. As well as IPCW and RPSFTM, two-stage adjustment has been used in HTA to adjust for switching. We need an understanding of the methods, so we can decide which one to believe, on a case-by-case basis. But first

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