Jneuroinflammation.biomedcentral.com

Impact of microbiota on central nervous system and neurological

WEBAbundant and diverse microbial communities coexist in humans and mice. Majority of these microorganisms including bacteria, archaea, fungi, and viruses reside …

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URL: https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1434-3

The function of gut microbiota in immune-related neurological …

WEBThe GI tract is a highly complex organ composed of microorganisms, the intestinal epithelium, and the mucosal immune system. The microorganisms living in the …

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Microglia in depression: an overview of microglia in the …

WEBMajor depressive disorder (MDD) is a public health problem that affects approximately 322 million people worldwide [].During the coronavirus disease 2019 …

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Inflammation: the link between comorbidities, genetics, and …

WEBAlzheimer’s disease (AD) is a neurodegenerative disorder, most cases of which lack a clear causative event. This has made the disease difficult to characterize …

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On inflammatory hypothesis of depression: what is the role of IL-6 …

WEBElevated levels of IL-6 in patients with COVID-19 infection. The world-wide effect of the coronavirus disease 2019 (COVID-19) pandemic is enormous and is not …

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The cerebrovascular and neurological impact of chronic smoking …

WEBTraumatic brain injury (TBI) has long been among the most common type of trauma and the leading cause of death and disability in the young-aged population (≤ 45 …

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Exercise suppresses neuroinflammation for alleviating Alzheimer’s

WEBAlzheimer’s disease (AD) is a chronic neurodegenerative disease, with the characteristics of neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although …

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The progress of gut microbiome research related to brain disorders

WEBBBB is a semipermeable barrier composed of specialized endothelial cells in the microvasculature [].The BBB separates the CNS from the peripheral blood [].There …

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Mitochondrial dysfunction in microglia: a novel perspective for

WEBAlzheimer's disease (AD) is the most common neurodegenerative disease in the elderly globally. Emerging evidence has demonstrated microglia-driven …

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Gut microbiota, circulating cytokines and dementia: a Mendelian

WEBSome studies have shown that gut microbiota may be associated with dementia. However, the causal effects between gut microbiota and different types of …

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Obesity-induced blood-brain barrier dysfunction: phenotypes and

WEBObesity, a burgeoning global health issue, is increasingly recognized for its detrimental effects on the central nervous system, particularly concerning the integrity of …

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Global, regional, and national burden of Guillain–Barré syndrome …

WEBOverview. This study is part of the GBD 2019 project, which was conducted by the Institute for Health Metrics and Evaluation (IHME) to provide a systematic …

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Peripheral blood amyloid-β involved in the pathogenesis of …

WEBAlzheimer’s disease (AD) is the most common age-associated dementia with progressive loss of memory and cognitive functions [].It is predicted that by 2050, …

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The peri-menopause in a woman’s life: a systemic inflammatory …

WEBThe peri-menopause or menopausal transition—the time period that surrounds the final years of a woman’s reproductive life—is associated with profound …

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NAD+ improves cognitive function and reduces …

WEBNAD + treatment mitigated impairment of learning and memory in CCH rats. The BCCAO model is a classic animal model that mimics CCH. After the BCCAO …

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Tau and neuroinflammation in Alzheimer’s disease: interplay …

WEBAlzheimer’s Disease (AD) contributes to most cases of dementia. Its prominent neuropathological features are the extracellular neuritic plaques and …

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Cyanidin-3-O-glucoside protects the brain and improves cognitive

WEBCyanidin-3-O-glucoside (C3G) is a natural anthocyanin with antioxidant, anti-inflammatory, and antitumor properties. However, as the effects of C3G on the …

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Central intracrine DHEA synthesis in ageing-related …

WEBIt is a well-known fact that DHEA declines on ageing and that it is linked to ageing-related neurodegeneration, which is characterised by gradual cognitive decline. …

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