Genome.cshlp.org

The NIH Human Microbiome Project

WebThe NIH HMP Working Group 1, ; Jane Peterson 2, 3, ; Susan Garges 3, ; Maria Giovanni 4, ; Pamela McInnes 5, ; Lu Wang 3, ; Jeffery A. Schloss 3, ; Vivien …

Actived: 9 days ago

URL: https://genome.cshlp.org/content/19/12/2317.short

Precision environmental health monitoring by …

WebLongitudinal profiling of the exposome and internal multi-omics to monitor personal environmental health. We investigated whether the external exposome is …

Category: Health Go Health

Microbial strain-level population structure and genetic …

WebWe introduce StrainPhlAn, a novel metagenomic strain identification approach, and apply it to characterize the genetic structure of thousands of strains from …

Category: Health Go Health

The NIH Human Microbiome Project

WebThe HMP is a limited effort per se, but has the ultimate objective of creating broad opportunities to improve human health through monitoring or manipulating the …

Category: Health Go Health

Mutations in Healthy Blood

WebApril 23, 2014 – Genetic mutations are commonly studied because of links to diseases such as cancer; however, little is known about mutations occurring in healthy individuals. In a …

Category: Cancer Go Health

Precision environmental health monitoring by …

WebAbstract. Conventional environmental health studies have primarily focused on limited environmental stressors at the population level, which lacks the power to dissect the …

Category: Health Go Health

A diversity profile of the human skin microbiota

WebThe many layers and structures of the skin serve as elaborate hosts to microbes, including a diversity of commensal and pathogenic bacteria that contribute to both human health …

Category: Health Go Health

Comprehensive analysis of structural variants in breast …

WebAbstract. Improved identification of structural variants (SVs) in cancer can lead to more targeted and effective treatment options as well as advance our basic …

Category: Cancer Go Health

Sex differences in human adipose tissue gene expression …

WebAbstract. Sex differences in adipose tissue distribution and function are associated with sex differences in cardiometabolic disease. While many studies have revealed sex …

Category: Health Go Health

A DNA Polymorphism Discovery Resource for Research …

WebThis DNA Polymorphism Discovery Resource will be immensely valuable for the discovery of human genetic variation, which other follow-up studies can relate to …

Category: Health Go Health

Co-expression networks reveal the tissue-specific regulation of

WebWe used the Genotype-Tissue Expression (GTEx) project v6 RNA sequencing data across 50 tissues and 449 individuals. First, we developed a framework called Transcriptome …

Category: Health Go Health

A transcriptome-based single-cell biological age model and …

WebAbstract. Accurately measuring biological age is crucial for improving healthcare for the elderly population. However, the complexity of aging biology poses challenges in how to …

Category: Health Go Health

A compendium of conserved cleavage and polyadenylation events …

WebHere, we present a compendium of conserved cleavage and polyadenylation sites (PASs) in mammalian genes, based on approximately 1.2 billion 3′ end sequencing reads from …

Category: Health Go Health

HiCanu: accurate assembly of segmental duplications, satellites, …

WebAbstract. Complete and accurate genome assemblies form the basis of most downstream genomic analyses and are of critical importance. Recent genome assembly …

Category: Health Go Health

Precision environmental health monitoring by longitudinal …

WebFigure 3. Precision environmental health network revealed by inter-omics analyses between the exposome and internal multi-omics. (A) Spearman's correlation network of all …

Category: Health Go Health

Letter A diversity profile of the human skin microbiota

Webrium, Kocuria, Propionibacterium, Microbacterium, and Micrococcus. OTUs and sequences identified in division Firmicutes (12% and 4.3%, respectively) were most commonly …

Category: Health Go Health

dbSNP—Database for Single Nucleotide Polymorphisms and …

WebdbSNP—Database for Single Nucleotide Polymorphisms and Other Classes of Minor Genetic Variation. Stephen T. Sherry 4, Minghong Ward, and. Karl Sirotkin. + Author …

Category: Health Go Health

A DNA methylation haplotype block landscape in human tissues …

WebYan Feng 1, ; Zhiqiang Zhang 2, ; Yuyang Hong 1, ; Yi Ding 1, ; Leiqin Liu 1, ; Siqi Gao 1, ; Hai Fang 2 and ; Jiantao Shi 1, 3; 1 State Key Laboratory of Molecular …

Category: Health Go Health

Genome wide analysis of 3′ UTR sequence elements and proteins

WebAbstract. Posttranscriptional regulation plays a crucial role in shaping gene expression. During the maternal-to-zygotic transition (MZT), thousands of maternal transcripts are …

Category: Health Go Health

Linking transcriptional and genetic tumor heterogeneity through …

WebAbstract. Characterization of intratumoral heterogeneity is critical to cancer therapy, as the presence of phenotypically diverse cell populations commonly fuels …

Category: Cancer Go Health

Rapid Amplification of Plasmid and Phage DNA Using Phi29 DNA …

WebAbstract. We describe a simple method of using rolling circle amplification to amplify vector DNA such as M13 or plasmid DNA from single colonies or plaques.

Category: Health Go Health

Research The human gut virome: Inter-individual variation …

WebWe purified virus-like particles (VLPs) from stool samples collected longitudinally from six healthy volunteers between the ages of 18 and 40 yr who had normal bowel frequency, …

Category: Health Go Health

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