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Genetics and Public Health

The role of public health is to ensure that the basic conditions required for people to be healthy are present. Until recently, public health focused mostly on … See more

Actived: 5 days ago

URL: https://atlasgeneticsoncology.org/teaching/30053/genetics-and-public-health

Nodular sclerosis classical Hodgkin lymphoma (NScHL)

WEBClassical Hodgkin lymphoma is a distinct neoplastic entity with heterogeneous epidemiological features. It accounts for approximately 10% of all malignant lymphomas …

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Mixed cellularity classical Hodgkin lymphoma (MCcHL)

WEBMC is a subtype of cHL characterized by diagnostic HRS cells in a mixed inflammatory back-ground without sclerosis. Mononuclear Hodgkin cells can be present. …

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Angiogenic factors and cancer therapy

WEBThe original idea of blocking tumor-derived angiogenic factors for cancer therapy was raised by Dr. Judah Folkman. In his conceptual paper, Folkman wrote "One approach to the …

Category:  Cancer Go Health

Soft tissue tumors: an overview

WEBLipoma. More than half the cases studied show an abnormal karyotype, mostly balanced translocation, as single abnormality. Three distinct clustering of breakpoints …

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A Proposal for Training Medical Students : Knowing and Caring for …

WEBIn an analytical survey of the handicapped population, it was shown for children that 56% are mentally handicapped, 7% are poly-handicapped, 18% have personality, conduct, or …

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del (5q) solely in Myelodysplastic syndrome

WEBRPS14 is a ribosomal gene located in commonly deleted region (CDR) of 5q. It encodes for a protein required for maturation of 40S ribosomal subunits. Patients with …

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Atypical Chronic Myeloid Leukemia (aCML)

WEBaCML is a chronic myeloproliferative disorder with a clinical and hematological picture similar to chronic myelogenous leukemia (CML) but lacking Philadelphia …

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Atlas of Genetics and Cytogenetics in Oncology and Haematology

WEBAtlas of Genetics and Cytogenetics in Oncology and Haematology

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Classical Hodgkin lymphoma

WEBHodgkin lymphoma(HL) has been classified into classical HL (cHL), which accounts for 95% of all HL cases, and the less common nodular lymphocyte predominant HL (NLPHL), …

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Genomic Imprinting

WEBGenomic imprinting: a mark about parental origin. Genomic imprinting is the biological process whereby a gene or genomic domain is biochemically marked with information …

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IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial)

WEBHuman Isocitrate dehydrogenase (IDH) occurs in three isozymes, IDH1, located in the cytoplasm, and IDH2 and IDH3 located in the mitochondria. IDH functions …

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Mixed phenotype acute leukemia (MPAL)

WEBDisease. Mixed phenotype acute leukemia (MPAL) is a rare disease and historically has been labeled by a variety of names including mixed lineage leukemia, …

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Inv(3)(q21q26) GATA2::MECOM t(3;3)(q21;q26) GATA2::MECOM …

WEBInv(3) and t(3;3) have been documented in de novo AML (in all FAB subtypes except M3), therapy related AML (t-AML), MDS, CML, more often in …

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del(5q) in myeloid neoplasms

WEBAdditional anomalies. By definition, an interstitial deletion of 5q must be the sole abnormality for 5q- syndrome. However, 5q deletion can be seen with other …

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Florid follicular hyperplasia PTLD

WEBPhenotypically, FFH PTLD cases show follicular hyperplasia and the size of the follicles varied, but they all contained large, polarized, germinal centers with many …

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+7 or trisomy 7 (solely)

WEBTrisomy 7 is a common finding in benign and malignant solid tumors, in several non-neoplastic lesions (for example, osteoarthritis and rheumatoid arthritis), and …

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