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Updates in chronic graft-versus-host disease

Chronic graft-versus-host disease (GVHD) is the leading cause of late morbidity and mortality after allogeneic hematopoietic cell … See more

Actived: 9 days ago

URL: https://ashpublications.org/hematology/article/2021/1/648/482938/Updates-in-chronic-graft-versus-host-disease

Non-Myeloablative Lymphodepleting Conditioning in Patients …

WebA total of 165 patients (male: 100, female: 65) were enrolled across seven studies from 1991-2010, all with metastatic melanoma except 13 patients with epithelial …

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Treatment of bleeding complications in patients on …

WebBleeding is the dominant adverse event of treatment with any anticoagulant. 1 Major bleeding complications such as intracranial hemorrhage (ICH) or massive …

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A program of transition to adult care for sickle cell disease

WebAmong individuals with SCD, a rise in mortality occurs in the early young adulthood years (ages 20 to 24 years) (), coinciding with the period in which they leave …

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Sickle Cell Disease in 2023: Laying the Foundation for Future

WebNovel, alternative gene editing approaches for SCD are also in various stages of clinical development, portending more curative-intent options in the future. 3, 4 …

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American Society of Hematology 2020 guidelines for …

WebThree of 19 recommendations immediately impact clinical care. These recommendations include: use of transcranial Doppler ultrasound screening and …

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Increasing access to allotransplants in the United States: …

WebAlthough allogeneic HCT is potentially curative for many patients with high-risk hematologic malignancies and other diseases, it is a highly specialized and complex …

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Patient blood management as the standard of care

WebBlood transfusion is one of the most common hospital procedures in developed countries, such as the United States and the United Kingdom. 2 Over 11.3 …

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New Health Care Policies in FY 2023 ASH Clinical News

WebThe legislation covers a variety of health care policies including Medicare, Medicaid, telehealth, and pandemic preparedness. One change enacted by the …

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Evidence-based management of pregnant women with sickle cell …

WebThis article describes how SCD is managed during pregnancy in the Western World, particularly in the United Kingdom. It aims to cover preconception screening and …

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Acute GVHD: think before you treat

WebThe grading criteria for aGVHD are well established for the skin, liver, and intestinal tract, with higher grades associated with worse transplant outcomes. 7 …

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How we evaluate and treat neutropenia in adults Blood

WebAbstract. Isolated neutropenia is a common clinical problem seen by primary care physicians and hematologists. The evaluation of neutropenia is dictated by the …

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The relationship between blood groups and disease

WebThe molecular basis of the ABO blood group system was elucidated in 1990. 7 The gene encodes a glycosyltransferase, which transfers N-acetyl D-galactosamine …

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Diagnosis and classification of myelodysplastic syndromes

WebAbstract. Myelodysplastic syndromes (MDSs) are neoplastic myeloid proliferations characterized by ineffective hematopoiesis resulting in peripheral blood …

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Clinical Impact and Outcomes of Socioeconomic Status on …

WebWe conducted an anonymous online survey of 1339 patients with sickle cell disease over two (2) years (2021-2023). The questionnaire inquired about how many …

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How to evaluate the patient with a suspected mast cell disorder …

WebMast cell disorders include mastocytosis and mast cell activation syndromes. Mastocytosis is a rare clonal disorder of the mast cell, driven by KIT D816V mutation in …

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American Society of Hematology 2018 guidelines for management …

WebVenous thromboembolism (VTE) is the third most common cardiovascular diagnosis, with an incidence rate of ∼1 in 1000 annually in middle age and increasing to …

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ASH ISTH NHF WFH 2021 guidelines on the management of von …

WebThese guidelines make key recommendations regarding prophylaxis for frequent recurrent bleeding, desmopressin trials to determine therapy, use of antiplatelet …

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Gynecologic Conditions and Anemia: What Can We Do About Iron …

WebHMB is underdiagnosed and is estimated to affect 18 to 38 percent of women of reproductive age, and may be higher in perimenopausal individuals. 4 Causes include …

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Acquired bleeding disorders in the elderly Hematology, ASH …

WebBleeding in an elderly patient is commonly iatrogenic. More than 2 million people in North America are treated with oral anticoagulation and many more are taking …

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