Acil.bwh.harvard.edu

Transitions from Impaired Respiratory Health to Lung Disease

WEBA public health strategy for chronic lung disease focused on disease interception mandates the detection of impaired respiratory health before chronic lung disease becomes …

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URL: https://acil.bwh.harvard.edu/transitions-impaired-respiratory-health-lung-disease.html

Undiagnosed Obstructive Lung Disease in the United States.

WEBWe tested the contribution of self-reported health status and comorbidity burden (exposure) to the odds of being undiagnosed using logistic models adjusted for demographics, …

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The American Lung Association (ALA) Lung Health Cohort

WEBPulmonary physicians and respiratory researchers define respiratory health as the absence of lung disease. This simplistic definition has limited the development of a robust …

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Applied Chest Imaging Laboratory

WEBThe Applied Chest Imaging Laboratory at Brigham and Women's Hospital, Harvard Medical School, is a multidisciplinary team dedicated to advancing quantitative research in the …

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Deep Functional Phenotyping of the ALA Lung Health Cohort

WEBAn individual can progress from ideal lung health, to an intermediate phenotype of impaired lung health, to chronic respiratory disease, yet this transition is poorly understood. A …

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Patterns of Cardiopulmonary health across the life course

WEBTo-date, our group has investigated the predictors and consequences of impaired lung health and HF, separately, in CARDIA. In this project, we will build upon our prior work …

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Defining Impaired Respiratory Health. A Paradigm Shift for …

WEBReyfman PA, Washko GR, Dransfield MT, Spira A, Han MLK, Kalhan R. Defining Impaired Respiratory Health. A Paradigm Shift for Pulmonary Medicine. Am J Respir Crit Care …

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Understanding airway mucus dysfunction in population-based …

WEBThe public health and clinical relevance of “mucus dysfunction” are better understood when one focuses on the clinical manifestations of this process —chronic cough and phlegm …

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Lifetime spirometry patterns of obstruction and restriction, and …

WEBMETHODS: Using z scores from spirometry measured at ages 7, 13, 18, 45, 50, and 53 years in the Tasmanian Longitudinal Health Study (n=2422), we identified six FEV1/FVC …

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Association between Cardiorespiratory Fitness and Lung Health …

WEBBenck LR, Cuttica MJ, Colangelo LA, Sidney S, Dransfield MT, Mannino DM, Jacobs DR, Lewis CE, Zhu N, Washko GR, Liu K, Carnethon MR, Kalhan R. Association between …

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The American Lung Association (ALA) Lung Health Cohort

WEBRead more about The American Lung Association (ALA) Lung Health Cohort. Dr. George R Washko. Associate Physician, Brigham and Women's Hospital Associate Professor of …

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Machine Learning Development for Subtyping COPD

WEBThis heterogeneity makes it difficult to predict health decline and develop targeted treatments for better patient care. To date, researchers have attempted to use standard …

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COPD Applied Chest Imaging Laboratory

WEBThe World Health Organization and the American Thoracic Society recommends that every individual diagnosed with COPD be tested for Alpha-1. For more information about …

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Transitions from Impaired Respiratory Health to Lung Disease

WEBUnderstanding of the Lungs through Image Intelligence. Raúl is co-director of the Applied Chest Imaging Laboratory, lead scientist at Brigham and Women's Hospital and …

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B cell-adaptive Immune Profile in Emphysema-predominant COPD

WEBIn Aim 1, we will test the hypothesis that B cell, lymphoid follicles (LFs), and B cell product counts, and specific LF B cell clonal and post-transcriptional changes are increased in …

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Alejandro A. Diaz Applied Chest Imaging Laboratory

WEBHe also investigates the respiratory health of the Hispanic/Latino population by analyzing large cohorts, such as the Study of Latinos and NHANES. Dr. Diaz has trained college …

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Lung Function Decline and Disease Risk from Young Adulthood to …

WEBDecline in FVC was associated with diastolic dysfunction (odds ratio, 3.39; 95% confidence interval, 1.37-8.36; P = 0.006). CONCLUSIONS: Patterns of loss of lung health are …

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Transitions from Impaired Respiratory Health to Lung Disease

WEBTransitions from Impaired Respiratory Health to Lung Disease. Grant support: 3R01HL122477. PI:

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Ravi Kalhan Applied Chest Imaging Laboratory

WEBDr. Kalhan's research focus is in respiratory epidemiology. He leads large-scale epidemiologic cohort studies focused on lifecourse transitions from respiratory health to …

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Researching COVID to enhance recovery (“RECOVER”): Adult Chest …

WEBThe American Lung Association (ALA) Lung Health Cohort; Researching COVID to enhance recovery (“RECOVER”): Adult Chest CT Reading Center; Prognostic Markers …

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The American Lung Association (ALA) Lung Health Cohort

WEBGrant support: NIH/NHLBI 1U01HL146408 Mutli-PI:Drs. Ravi Kalhan, Mercedes R Carnethon, Elizabeth A Sugar and Dr. George R Washko

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Patterns of Cardiopulmonary health across the life course

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