Neural Health Model For Aging

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Human neurons to model aging: A dish best served old

(3 days ago) Web1. Introduction. Aging is one of the most fundamental biological processes, and by far the most crucial risk factor for several human age-associated diseases, including cancer, cardiovascular diseases, diabetes and neurodegenerative diseases [].As the numbers of …

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863511/

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Lessons from inducible pluripotent stem cell models on

(Just Now) WebHere, we review the evidence of cellular senescence in neuronal aging and disease, discuss human pluripotent stem cell-based model systems used to investigate …

https://www.nature.com/articles/s43587-024-00586-3

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Cellular reprogramming as a tool to model human aging …

(Just Now) WebFig. 1: Modeling human aging with iPSCs. A Strategies to model human aging by (i) inducing aging in iPSC-derived cells, (ii) iPSCs from patients with aging …

https://www.nature.com/articles/s41467-024-46004-5

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Neural mechanisms of ageing and cognitive decline Nature

(3 days ago) WebAgeing in humans is accompanied by stereotypical structural and neurophysiological changes in the brain and variable degrees of cognitive decline. …

https://www.nature.com/articles/nature08983

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The Overview of Cognitive Aging Models SpringerLink

(1 days ago) Web1 Introduction. A major challenge for cognitive aging researchers is to understand the causes of the age-related decline in cognitive function and the underlying …

https://link.springer.com/chapter/10.1007/978-981-99-1627-6_4

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The multifactorial nature of healthy brain ageing: Brain …

(7 days ago) WebThe World Health Organisation (WHO) This notion epitomizes the influential model proposed 25 years ago by Rowe and Kahn (Rowe and Kahn, 1997), Editorial …

https://www.sciencedirect.com/science/article/pii/S1568163723000983

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Neuronal Regulation of Aging - Harvard T.H. Chan School of …

(7 days ago) WebWe study signals that link neuronal energy and nutrient sensing in the brain to systemic modulation of the rate of aging. SnapShot: Neuronal Regulation of Aging. Weir HJ, Mair …

https://www.hsph.harvard.edu/mair-lab/neuronal-regulation-of-aging/

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Cognitive reserve and the neurobiology of cognitive aging

(7 days ago) WebNeuronal loss is no longer considered to be as extensive within or among individuals as previously supposed (Morrison and Hof, 2003); the aging brain is capable …

https://www.sciencedirect.com/science/article/pii/S1568163704000273

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Adult neurogenesis and aging mechanisms: a collection of insights …

(Just Now) WebAgeing. Neural stem cells. Adult neurogenesis supports important brain functions, such as learning and memory, and its decrease during aging may contribute …

https://www.nature.com/articles/s41598-023-45452-1

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Linking cognitive integrity to working memory dynamics in the …

(3 days ago) WebAging is accompanied by a decline of working memory, an important cognitive capacity that involves stimulus-selective neural activity that persists after stimulus …

https://www.jneurosci.org/content/early/2024/05/15/JNEUROSCI.1883-23.2024

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25 years of neurocognitive aging theories: What have we learned?

(8 days ago) WebThe past 25 years have provided a rich discovery of at least four fundamental patterns that represent structural and functional brain aging across multiple …

https://www.frontiersin.org/articles/10.3389/fnagi.2022.1002096/full

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Aging and Rejuvenation of Neural Stem Cells and Their Niches

(6 days ago) WebAging impairs brain function and is associated with neurodegenerative disorders and cognitive decline. Brunet and colleagues review how aging affects neural …

https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(20)30340-4

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Diet & Aging Brain, Sensory Systems Jean Mayer USDA Human …

(5 days ago) WebThe effects of diet and aging on mechanisms relevant for brain and sensory functions in response to diet and aging will be evaluated across multiple model systems, including …

https://hnrca.tufts.edu/research/research-directives/diet-aging-brain-sensory-systems

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Predicting Risk of Alzheimer’s Diseases and Related …

(5 days ago) WebRecent advancements in deep learning offered neural networks with a stronger capacity to understand the EHR14–17. A graph neural network, taking the …

https://www.medrxiv.org/content/medrxiv/early/2024/04/27/2024.04.26.24306180.full.pdf

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Aging and Rejuvenation of Neural Stem Cells and Their Niches

(7 days ago) Webopen archive. Aging has a profound and devastating effect on the brain. Old age is accompanied by declining cognitive function and enhanced risk of brain diseases, …

https://www.sciencedirect.com/science/article/pii/S1934590920303404

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The neural economics of brain aging Scientific Reports - Nature

(Just Now) WebReductionist molecular models of aging woefully fail to address neurological function 17; conversely, approaches at the level of function without backing in underlying …

https://www.nature.com/articles/s41598-021-91621-5

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Examining dynamic developmental trends: the interrelationship …

(2 days ago) WebBackground The objective of this research is to investigate the dynamic developmental trends between Age-Friendly Environments (AFE) and healthy aging in …

https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-024-05053-7

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Quantum mechanics-based deep learning framework considering …

(Just Now) WebA DNN, a general neural network model without stochastic process modeling for weights, was chosen to compare the analysis performance of DNN. RBF is a type of …

https://link.springer.com/article/10.1007/s10489-024-05465-3

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Neural plasticity in the ageing brain Nature Reviews Neuroscience

(9 days ago) WebFull size image. In 1955, Brody was the first to suggest that age-related reductions in brain weight were due, in part, to a decline in neuron number in all cortical …

https://www.nature.com/articles/nrn1809

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Dose-Response after Low-dose Ionizing Radiation: Evidence …

(5 days ago) Webthis, our pilot study introduces a novel approach using a data-driven deep neural network for health risk estimation. The deep neural network (DNN) model …

https://www.medrxiv.org/content/medrxiv/early/2024/04/12/2024.04.09.24305578.full.pdf

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Models and theories of health behavior and clinical interventions …

(3 days ago) WebBackground: Historically, influential models and theories of health behavior employed in aging research view human behavior as determined by conscious …

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549388/

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Neural ageing - Latest research and news Nature

(5 days ago) WebNeural ageing is the process by which neural cells in the brain and peripheral nervous system deteriorate structurally and functionally over time. It is associated with a …

https://www.nature.com/subjects/neural-ageing

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Aging datasets of commercial lithium-ion batteries: A review

(2 days ago) WebCreating precise and data-driven battery aging models has emerged as a prominent focus within the research community [1–11]. The accuracy of predictions related to a battery's …

https://ui.adsabs.harvard.edu/abs/2024JEnSt..8310560M/abstract

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Dynamics of cognitive variability with age and its genetic - Nature

(Just Now) WebHere, to address this gap, we cognitively profiled 21,051 people aged 17–85 years as part of the Genes and Cognition cohort within the National Institute for Health …

https://www.nature.com/articles/s41591-024-02960-5

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